Acepromazine is a tranquilizer commonly used to sedative for anxious dogs, or to help pets stay calm post-operatively or during stressful events. It is usually prescribed short-term, such as immediately after surgery, to ensure your pet rests adequately and does not harm themselves during recovery.
Dose Recommendation
Acepromazine can be given as needed, up to every 6 hours to keep your pet calm. Dogs’ sensitivity to this medication can vary, so your veterinarian may recommend starting at a lower dose. The medication typically takes 30–60 minutes to take effect after oral administration.
Possible Side Effects
- Sedation and weakness:Â This is sometimes pronounced. Reducing the dose or stopping the medication usually resolves these effects.
- Low blood pressure and slow heart rate:Â This most commonly appears as lethargy or weakness.
- Excitability:Â Rarely pets may show aggression, biting/chewing, or increased nervousness.
Additional Information
Despite historical concerns, acepromazine does not lower the seizure threshold and has been shown to be safe in dogs with seizures.
Dogs with the MDR-1 mutation or certain sighthound breeds may be more sensitive to acepromazine, so starting at a lower dose is recommended.