Midazolam is an injectable medication that can be given intranasally (in the nose) during cluster seizures. It may be provided as a liquid or gel. This method is the fastest at-home way to stop seizures, usually working within 5–10 minutes and lasting for about 2 hours. It is especially useful in emergencies when IV access is not available. Midazolam is stronger than clorazepate but has a shorter duration of action.
Dosing
Give midazolam in the nostril after the first seizure at home. If the volume is large, it can be split between both nostrils. It is best to wait until the seizure has ended before administering the medication—both to avoid being bitten and because its purpose is to prevent additional seizures, not stop the one that is already happening. Midazolam can be given up to 3 times in 24 hours, waiting at least 5 minutes between doses. If your pet continues to have seizures after 3 doses, please call Neuro Vet to determine if your pet should be seen on an emergency basis.
Possible Side Effects
Side effects only occur while your pet is receiving the medication:
- Sedation and wobbliness:Â Pets may appear very drowsy or unsteady, sometimes bumping into walls. This usually resolves within minutes to hours.
- Paradoxical stimulation:Â Some pets may instead show anxiety, pacing, or panting. This also typically resolves within minutes to hours.